Mediterranean Tropical Like Cyclones, also known as medicanes, are small cyclones that are observed in the Mediterranean region with a frequency of 1-2 cases per year, mainly in autumn and winter. The tropical-like phase of these cyclones is characterized by the presence of a symmetric thermal structure and a deep warm core, which are features typical of tropical cyclones. The mechanisms of formation and tropical transition have been investigated by many authors, but a definition of medicane has not been found yet due to the strong case-dependency. In this work 17 cyclones, including three potential medicanes in 2023, have been analyzed using the ERA5 reanalysis dataset. Some general properties in the lower and upper troposphere have been investigated considering that winter cyclones have a lower dynamic tropopause than autumn cyclones. Results shows that during the deep warm core phase there is an overall negative correlation between the parameter −VTU and PV in the upper troposphere, while PV increases in the low troposphere due to latent heat release. It has also been verified that during the tropical-like phase the wind shear presents lower values, the jet stream is weaker and farther from the cyclone center, and the cyclone is vertically aligned, even if some exceptions exist. Then, the presence of a dry intrusion has been investigated using back-trajectories, showing that all cyclones present descending dry air associated with a PV streamer, meaning that the upper-level dynamics are fundamental in early stages. However, the threshold of 400 hPa of descent in 48 hours used in literature to define the dry intrusion is not appropriate for the cyclogenesis in the Mediterranean, and in some cases a weaker PV streamer associated with a less pronounced descent is sufficient for the cyclogenesis. Finally, the cyclone Ianos, one of the strongest medicane ever recorded, presents two weak descending flows associated with PV streamers, one in the early stage and one before the strong deep warm core phase. This cyclone has been analyzed through the pressure tendency equation (PTE) to quantify the role of the upper-level dynamics and of the diabatic heating on the surface pressure tendency. The same tool has been used to analyze the recent cyclone Daniel that affected Libya in September 2023, and a comparison with Ianos has been performed.