The first lead(II) borosulfate Pb[B2(SO4)4] was synthesized under harsh conditions via a solvothermal reaction of PbO2 with H3BO3 and oleum (20 % SO3). The compound crystallizes in the orthorhombic space group Pnna (no. 52) with the lattice parameters a = 1251.6(7), b = 1252.1(7), and c = 730.2(4) pm (Z = 4). The structure of Pb[B2(SO4)4] is constructed of one‐dimensional infinite anionic chains according to 1∞[B(SO4)4/2]- and charge compensated by Pb2+ cations, which are coordinated to the chain terminating oxygen atoms of the (SO4) tetrahedra. The lone pair of electrons of the Pb2+ cations is sterically not active. Pb[B2(SO4)4] was characterized by means of single‐crystal and powder X‐ray diffraction, as well as vibrational spectroscopy.